After being fired, I became the light of medicine

Chapter 162: Simulation Laboratory Automatic Hang Up!
In the next few days, with the help of Zhang Yang, the first project team made rapid progress in the research and development of "sAC cyclase activity generator".

More than a dozen "lead compounds" that are effective against the target were "accidentally" discovered one after another, and then quickly assigned to scientific researchers for the next step of re-screening.

of course,

Although Zhang Yang knew which "compound" was the most effective, it was impossible for him to directly tell the R&D personnel the correct answer among the dozen or so "lead compounds".

In the following days, he would come to the first project team every few days to learn about the research and development progress, and by the way, put forward some "valuable suggestions" to quickly help the research and development team narrow the scope.

It is no exaggeration to say that his opinions helped the first project team reduce the research and development time by at least 1-2 years!

While helping the first project team to develop the "sAC cyclase activity generating agent", Zhang Yang was also busy.

After learning that the research and development time rate of the "simulated laboratory" was as high as 1:10, he excitedly prepared to start the research and development of another infertility drug in the "simulated laboratory", that is, a drug to treat "teratozoospermia".

Since this drug involves multiple male hormones and covers multiple organs such as the pituitary gland and testicles, its pathological mechanism is complex and it is very difficult to develop.

Therefore, even the R&D center of Qingshan Pharmaceutical had no project team willing to take over.

Now, he simply conducts research and development in a "simulation laboratory", starting from scratch, starting with finding drug targets.

One day, two days, three days.

Zhang Yang immerses himself in the simulator every night, intensively searching for drug targets for teratozoospermia.

But on the fourth day, he began to feel that the intensity was too great, especially after eight hours of high-intensity simulation overnight. His brain did not get any rest, and he felt very depressed the next day.

He has realized that if he were just a simple drug developer, the 1:10 time rate in the simulation laboratory would undoubtedly give him an extra advantage, and the various new drug projects on hand would be successfully developed at an unexpected speed.

but.

After all, he is the boss of Qingshan Pharmaceutical. He has to deal with the affairs of Qingshan Pharmaceutical during the day, and he always needs to rest at night.

"It seems that this function is still a bit useless. It would be better if it could be developed independently."

"I set the research and development direction and experimental content myself, and then simulate the laboratory to conduct data experiments according to my own ideas and directions, and finally obtain experimental data."

"Just like in reality, you only need to make arrangements, and the R&D team will give you the final test results according to your ideas!"

"It's a pity that this simulator is still a little inferior. I have to do it myself."

The sigh echoed in the simulation laboratory, but just as the voice fell, the system voice suddenly sounded:
"Dear host, hello, this simulation laboratory has opened the automatic hosting research and development function."

"You only need to set the R&D direction and test content on the console, and the simulation laboratory will simulate according to your ideas."

Zhang Yang was stunned, and then he was pleasantly surprised!
Is there really such a function?!

In this case, doesn’t it mean that I only need to provide the research and development direction, and the process can be left to the simulation laboratory to simulate slowly?

This is such an easy way!

Thoughtful! Really thoughtful!

However, he soon realized that if he wanted to simulate the automatic development of the laboratory, he would probably need to pay energy points.

"You need energy, right?"

"Yes, host. The simulation laboratory can host research and development for up to 10 hours a day, and 1 energy point is required every hour."

“The simulation is as efficient as doing it yourself.”

really.

Zhang Yang couldn't help but shake his head. There really is no free lunch in the world.

This is equivalent to spending 10 energy points to hire a "self" to conduct a ten-hour experiment...

However, even though the joy in my heart was somewhat diluted, I still had to sigh that the functions of the "Simulation Laboratory" were really comprehensive.

Compared with the previous one-time payment of 50 or 100 points, which was completely dominated by the system to conduct a "lottery-style" breakthrough simulation, this method takes longer.

But as long as your research and development direction is correct, you should be able to save a lot of energy.

Of course, the premise is that the research and development direction is correct.

Thinking of this, Zhang Yang immediately paid 10 energy points, and then set his target search direction for the "teratozoospermia" drug.

Soon a prompt sound came from the system.

"Congratulations to the host for the successful payment. The simulation laboratory will immediately conduct simulation according to the research and development direction required by the host."

"This time, 10 energy points are consumed. Please check the results of this simulation test in ten hours."

"You currently have 190 energy points remaining."

"I spent another 10 points..."

Seeing that 10 energy points had been consumed again, Zhang Yang felt both painful and happy. The energy points were so useful!
He immediately thought of the system's prompt yesterday and wanted to obtain energy points:
The first is to complete the "plot simulation";
The second is to complete the research and development tasks issued by the "Simulation Laboratory";

The third is to provide the "simulation laboratory" with complete drug data patented by the host.

Currently, there are no new plots or tasks for the first and second methods, so the only way to obtain energy is the third method.

For example, "ITG human myelopoietin" is provided by the simulator itself, so it is naturally impossible to share it with the simulator.

Qingshan Pharmaceutical independently developed...

There are only the "macromolecule toxin catalyst" that was bought out from BI and the "sAC male contraceptive" that was just developed independently.

In accordance with the requirements of the simulator, Zhang Yang quickly uploaded the compound patents, crystal form patents, animal experiment data and other information of the two drugs.

About five seconds later, a clear prompt sounded:
"'Macromolecule Toxin Catalyst' has been successfully shared and entered into the 'Simulated Laboratory Drug Database'!"

"This drug is considered a Class C auxiliary treatment drug, mainly used as an auxiliary agent for kidney dialysis. The reward energy value is 400 points. (Initial value 300 points + floating value 100 points.)"

"'sAC male contraceptive pill' has been shared successfully and has been entered into the 'simulated laboratory database'!"

"This drug is classified as a Class C auxiliary drug, mainly used for male contraception. The reward is 300 energy points."

"You currently have 890 energy points remaining."

Both drugs are only Class C drugs...

and!

The energy value of this reward is too little. The two drugs are worth only 700 points in total. You should know that the previous breakthrough in the research and development of "sAC cyclase activator" in the simulator used 50 points for 800% of the semi-finished products!
"Never mind. The energy value reward should be that the rarer the medicine, the better the effect, and the higher the level, the more valuable it is!"

"When Qingshan Pharmaceutical R&D Center is able to develop targeted drugs such as cancer drugs, the rewarded energy value should be higher!" After discovering the automatic hanging function of the simulation laboratory, Zhang Yang's efficiency increased significantly in an instant.

Every morning he would pay 10 energy points to start the simulation, and then wait until the next morning to check the research and development results of the previous day.

During the research and development process, he checked the test results while adjusting his research and development ideas based on the test data, just like real research and development.

Of course, he can also use the simulation laboratory to pay 50 energy points at a time for "rapid target exploration".
But Zhang Yang has already asked the system. The more complex the disease, such as teratozoospermia and azoospermia, whose pathological mechanisms are not yet clear, the more data needs to be simulated.

It is often not possible to find the target in one, two or ten attempts.

Unless you are the emperor of Europe.

The "teratozoospermia" project was not urgent, and Zhang Yang did not want to take a chance, so he simply carried out drug development in the traditional way.

Before he knew it, ten days had passed and Zhang Yang had already paid 100 energy points.

Ten days means 100 hours, which is 1000 hours in real time.

Calculated based on 8 hours per working day, Zhang Yang has spent 125 working days, or 4 months, on research and development, and the research and development data he has obtained is indeed roughly the same as the actual progress of 4 months.

Although the exact target for teratozoospermia has not yet been discovered, there are already some clear ideas.

While Zhang Yang was exploring the target of "teratozoospermia", he also continued to follow up on the development of "sAC cyclase" for the treatment of asthenozoospermia at the Qingshan Pharmaceutical Drug Research and Development Center.

The progress of "sAC cyclase activator" has been narrowed down to only a few "lead compounds" that need to be screened. The next step is to "optimize the molecular structure of the compound" and then start animal experiments.

While Zhang Yang was busy on both ends, Liu Qiang and Xu Min also experienced an unforgettable month.

To be precise, they had not even waited a month. On the 28th day, the two of them could not wait to make another appointment with Dr. Feng Yan, their previous expert.

When they arrived at the Reproductive Technology Department of Chengdu Third People's Hospital again, their mood was completely different from a month ago.

Over the past month, they have learned more about infertility from the Internet, and the more they read, the more worried they become!
In particular, when the two saw on the Internet a patient who had almost the same "asthenozoospermia" and "severely deformed sperm" as Liu Qiang and could not even successfully conceive through in vitro fertilization, they were completely panicked.

What if IVF fails to produce pregnancy?
Don’t you want to have children for the rest of your life?
Standing at the entrance of the Reproductive Technology Department, Xu Min looked at the rather nervous Liu Qiang and comforted him:
"Don't worry too much, husband. We have been taking care of it for a month, so it should be getting better."

"Ah."

Liu Qiang breathed a sigh of relief, and after a while, the two of them met Dr. Feng Yan.

The process was the same as last time. I first collected sperm for testing and the results came out an hour later.

In the outpatient clinic, Doctor Feng Yan looked at the test results in front of her, then pulled up the results from a month ago on the computer for comparison and frowned slightly.

"Liu Qiang, the results of your examination last month: only 286 of the 2 sperms were normal in shape, and the remaining 284 were all deformed; and the rate at which all the sperm could move forward in a straight line was 0."

"This time, not only is the ability of sperm to move forward in a straight line still less than 1%, but the sperm abnormality rate has not improved. There are only two sperm with normal morphology out of sperm."

"This situation..."

As she spoke, Feng Yan's eyes first swept over Xu Min and finally fell on Liu Qiang.

"If you want to have a child in this situation, you can only consider IVF."

In vitro fertilization!

When these four words came out of the doctor's mouth, even though they were mentally prepared, Liu Qiang and even Xu Min couldn't help but tremble in their hearts, and an indescribable sadness surged in their hearts.

Especially Liu Qiang,
He lowered his head slightly, his eyes dropped to his chin, and his face was full of sadness.

In the past month, he has been exercising every day, running instead of sitting for long periods of time, and going to bed at 9 o'clock in the evening. He is hoping that this examination will show improvement and that there will be some hope.

But unexpectedly, there was no improvement!
After a full thirty seconds of silence, Liu Qiang sighed heavily:
"Doctor, I understand. I also saw on the Internet that my problem is quite serious."

"However, I still find it hard to accept IVF. Many people on the Internet say that I can try artificial insemination first. I think..."

"You want to try artificial insemination first?"

Liu Qiang nodded.

First of all, he still hopes to have a normal pregnancy.

Secondly, he had learned about the cost of artificial insemination, which was about 7000 yuan per time, while in vitro fertilization was much more expensive.

However, Doctor Feng Yan simply shook her head and refused:

"You should know what artificial insemination is, right?"

"It is to use professional instruments to screen out sperm that meet the requirements and concentrate the sperm with vitality;

These viable sperm are then transported to the female uterine cavity through the 'insemination catheter' to combine with the egg."

"Generally speaking, if the sperm activity is low and the deformity rate is not too high, we will consider letting the patient do 'artificial insemination'."

"But your situation..."

Feng Yan paused and exhaled softly:

"To be honest, artificial insemination is not suitable for you. Although you have normal sperm, the activity is too low and the quantity is too small!"

"In your case, you can only do second-generation IVF, and even then you may not get pregnant!"

Doctor Feng Yan's words completely shattered the last bit of fantasy the two had.

After a long while, Xu Min, who had been silent, looked anxious and clearly in a state of panic that she could not suppress:
"Doctor, we want to have a child, and we are willing to do IVF."

"If we do IVF, what is the success rate for a situation like ours?"

Feng Yan's expression also eased and he explained:
"IVF has now developed to the third generation."

"The first generation of test-tube babies can be understood as the normal combination of male sperm and female eggs, which is to allow them to fertilize naturally in an in vitro culture dish."

"For the second generation of IVF, for patients like you who have severe asthenozoospermia and severe teratozoospermia, our medical staff will precisely inject the sperm into the cytoplasm of the egg."

"Third-generation IVF is mainly used for couples with genetic diseases, such as albinism, etc.... You don't consider this!"

"However, you must be mentally prepared. Even if you do the second-generation test tube, the success rate is not high, and the cost is relatively high!"

Xu Min was slightly startled, hesitated for a moment, and looked at Feng Yan with a sad look:

"Doctor, how much is it? Can it be reimbursed?"

(End of this chapter)