After being fired, I became the light of medicine

Chapter 142: Overseas Pricing of Kidney Toxin Clearing Dialysis Needles (Subscription Request)
Zhang Yang prepared two actions.

First, find out as quickly as possible whether BI's "Toxin Catalyst" and "Kidney Toxin Clearing" combined medication is effective. This is what Zhang Yang values ​​most and is the most important part of this plan.

After all, the "BI-toxin catalyst" is already a ready-made semi-finished product and is most likely to be quickly applied in clinical practice.

Second, Tsingshan Pharmaceutical has begun to develop similar "large molecule toxin decomposition catalysts" on its own, but this is only an alternative option.

These two tasks were not strange to Fang Hanliang. Even the first imitation of BI's "toxin catalyst" was not uncommon in the medical field.

In fact, in the field of pharmaceutical research and development, many pharmaceutical companies competing for the same target will imitate and study each other's drugs during the research and development process, so as to obtain some inspiration and research and development ideas from their competitors.

To talk about more recently, when Novartis was preparing to be the agent for the "hepatocyte activator", it also carried out ingredient analysis in the laboratory after obtaining samples from Tsingshan Pharmaceutical, and only started to apply for clinical trials after ensuring that it had a certain therapeutic effect.

Anyway,

All drug patents are public. As long as the patented drugs are not used publicly for commercial activities, no one can interfere if they are secretly imitated to understand the drug's effects or to gain inspiration.

Of course, Tsingshan Pharmaceutical can also use the crystal form patent of "BI-toxin catalyst" to roughly imitate drugs with similar effects, thereby gaining a deeper understanding of the "toxin catalyst".

Fang Hanliang quickly clarified his next work tasks, but just as he was about to leave, Zhang Yang suddenly called him.

"By the way, Fang Bo, you were setting up a research and development team some time ago. Have you selected all the personnel?"

"Is there still a shortage of people?"

Fang Hanliang stopped and turned around:
"It's almost done, what's wrong?"

A smile appeared on Zhang Yang's face.

He thought of Zhou Xiaomei whom Ren Xiaomin had mentioned before.

Last month, he met Zhou Xiaomei several times in the drug research and development center. Just as Ren Xiaomin said, girls change a lot when they grow up.

Not only is she much prettier than she was in high school, but her figure has also fully grown into a slender and graceful girl with curvy figure.

However, at that time, considering that Zhou Xiaomei had just graduated from college and was not yet able to take on the work of the R&D team, she was asked to work as a "handyman" in the drug R&D center first. She would help any R&D team that needed help and get familiar with the basic work as soon as possible.

Now that a month or two have passed, it is time to arrange for Zhou Xiaomei to join Fang Bo's new team, and work seriously and systematically from the bottom up as a "laboratory assistant", and carefully learn the entire process of drug research and development.

This is of great benefit to Zhou Xiaomei's development and growth.

Thinking of this, he said:

"It's like this, I want to introduce someone to your R&D team."

"She is a freshly graduated undergraduate with no work experience. Of course, you don't need to assign her any special tasks. Just let her start from the lowest level as a 'laboratory assistant'."

Fang Hanliang was slightly stunned.

To be honest, in the field of biopharmaceuticals, undergraduates are not even close to his expectations.

However, since Zhang Yang had asked personally, he agreed after a little thought.

"Okay, Mr. Zhang, what's her name? I'll go back and look at her information."

"Call……"

Zhang Yang just said this, then changed his mind:
"Forget it, I'll go to the R&D center with you. I haven't seen her for a long time."

"Ok."

The drug research and development center is about 150 meters away from the office building. Five minutes later, the two stepped into the gate of the research and development center.

The R&D center has a total of four floors. There is a large conference room on the first floor. On both sides of the conference room are several medium-sized office areas of about 200 square meters, which are used as office spaces for each project team.

Team project leaders like Fang Hanliang have their own independent offices, which are also located at the innermost part of the first floor.

The second and third floors are various large, medium and small laboratories, including basic chemistry laboratories, biology laboratories, animal laboratories, pharmacology laboratories, etc., about twenty in total.

The top floor is where test supplies and experimental data are stored.

Zhang Yang asked Fang Hanliang to go to the office first, and then he went to the second floor to look for Zhou Xiaomei.

After asking two colleagues along the way, I finally found Zhou Xiaomei cleaning laboratory utensils in an empty "chemical laboratory" on the second floor.

He was not surprised, because what Zhou Xiaomei did was what every "biology major" graduate had to go through.

Even he started out as a "lab assistant", doing the most basic jobs such as cleaning utensils, recording data, and cleaning the laboratory.

"Little sister Zhou."

The quiet laboratory was suddenly broken by a low voice. Zhou Xiaomei turned her head and when she saw that the person calling her was Zhang Yang, her face was filled with surprise.

"boss Zhang?!"

Seeing Zhou Xiaomei looking a little flustered and even at a loss as to what to do, Zhang Yang couldn't help but smile.

He had seen Zhou Xiaomei a few times in the past few days, but he just nodded to her from a distance. This was the first time they stood so close to each other and chatted alone like today.

"Put the test tube aside for now and come back to wash it later. Please accompany me to the office first."

"Oh."

Although Zhou Xiaomei was surprised, she quickly turned around, washed the test tube in her hand quickly, and then hung it aside.

"Okay, Mr. Zhang."

"Ah."

The two walked out of the laboratory quickly. Looking at the familiar yet somewhat unfamiliar Zhou Xiaomei, Zhang Yang couldn't help but say:

"Little sister, you've been in the company for almost two months, right? How is it? Are you used to it?"

"Yeah, I'm quite used to it." Zhou Xiaomei said in a low voice.

Zhang Yang could sense that Zhou Xiaomei was somewhat afraid of him, but he did not say it out loud and continued:
"That's good. I heard from Brother Ren that you were going to take the postgraduate entrance exam. Are you preparing for it? If you have any difficulties, you can come to me directly."

"Well, thank you Mr. Zhang and Mr. Ren for your concern. I'm preparing now. I'm doing fine at the moment. There are no difficulties!"

"it is good."

Zhang Yang nodded slightly, looked at Zhou Xiaomei, and slowed down his pace:
"The main reason I came to see you today is because I haven't arranged a job for you before."

"The company is currently forming a new R&D team for kidney drugs. I am planning to recommend you to Dr. Fang. You can follow Dr. Fang and learn the R&D process in a comprehensive and systematic manner."

“This will be of great help to your future development.”

There was a hint of surprise in Zhou Xiaomei's eyes. She certainly knew that Dr. Fang was forming a research and development team.

However, Dr. Fang has very high standards. Not only does he only select senior colleagues with sufficient R&D experience in the R&D center, but he also only recruits industry backbones with more than ten years of experience in the R&D of "kidney drugs".

She never thought that she could join Dr. Fang's R&D team.

After a moment, she looked up at Zhang Yang, then lowered her head and whispered:

"Thank you, Mr. Zhang."

Zhang Yang does not have as delicate a mind as Zhou Xiaomei.

"Don't call me Mr. Zhang all the time. Just call me Zhang Yang."

As he said this, he also sighed:

"Before you know it, you've graduated from high school and are working."

"Come to think of it, I have watched you grow up..." Zhou Xiaomei lowered her head and listened quietly to Zhang Yang. Soon the two of them came to Fang Hanliang's office.

Zhang Yang did not hesitate to introduce:

"Fang Bo, this is the person I recommend to you. Her name is Zhou Xiaomei."

After saying this, he looked at Zhou Xiaomei:
"Little sister, you should work hard in Fang Bo's team from now on."

"Fang Bo is a well-known expert in the entire industry. You can learn a lot from him. Of course, I also told Fang Bo to start with the position of 'lab assistant' and learn well."

"OK, all right."

Zhou Xiaomei looked up at Fang Hanliang, and her eyes no longer showed the shyness and embarrassment she had just felt when facing Zhang Yang.

Although she was still a little nervous, she said generously:
"Dr. Fang, I will trouble you from now on. Please tell me if you need anything, and please correct me if I do anything wrong!"

"Okay, okay, it's no trouble."

After a brief introduction, Zhou Xiaomei tactfully prepared to leave.

She looked at Dr. Fang, and finally her eyes stopped on Zhang Yang.

"Dr. Fang, Mr. Zhang, you guys chat, I'll be leaving first."

"it is good."

Zhou Xiaomei opened the office door and walked out. When the door closed again, she finally breathed a sigh of relief.

Suddenly, the corners of her mouth couldn't help but rise up happily, and her face was full of sweet smiles, as if everything in front of her had become so beautiful at this moment.

"Thank you, brother."

……

After arranging the imitation of BI's "toxin catalyst", Zhang Yang handed it all over to Fang Hanliang.

Fang Hanliang originally worked at BI Company. Although he did not participate in the research and development of "BI-Toxin Catalyst", his more than ten years of work experience also allowed him to know some details and inside stories that outsiders did not know.

In addition, after Zhang Yang asked Lucas from GlaxoSmithKline to help get some samples of the "toxin catalyst" that BI was conducting phase II clinical trials, the work on understanding the "toxin catalyst" progressed exceptionally smoothly.

One month, two months,

Just when Fang Hanliang was constantly analyzing the real data of the "toxin catalyst", GlaxoSmithKline and Novartis were the first to bring news.

The clinical trial of "Kidney Toxin Clearing" conducted by GlaxoSmithKline in India has been approved by the local regulatory authorities in the UK and is allowed to be produced and marketed.

The situation is basically the same for Novartis. Although the progress is slower, it can also start to set the agency price of "Shenduqing".

Both Lucas and Friedman flew to Tsingshan Pharmaceutical in person and also brought basic dialysis costs from their respective countries.

The United Kingdom is an old capitalist country with a strong foundation. In 1948, when the British Empire had not yet completely declined, it launched a universal free health care system, which was also the first universal free health care system in the world.

According to data provided by Lucas, the annual cost of dialysis in the UK is approximately 25000 pounds, equivalent to 175 pounds per time.

These costs will be fully covered by the UK NHS (Health Insurance).

Zhang Yang positioned the "Kidney Toxin Clearing Dialysis Needle" as a dialysis substitute, so the price cannot be much higher than the dialysis cost.

After consulting with Lucas, he decided to set the price in the UK at £192, 15% more expensive than traditional dialysis models.

Of course, considering that GlaxoSmithKline agents also need to make money, Tsingshan Pharmaceutical's agency shipping price is 135 pounds, equivalent to RMB 1300 per injection.

As for other parts of the EU, the cost of dialysis is similar to that in the UK. The cost per injection in the entire EU is basically around 200-250 pounds.

After dealing with the UK, the situation in the US becomes much more complicated.

The United States does not have free health care for all. If you have insurance, such as participating in federal Medicare, after deducting the $150 deductible, the patient will pay 20% of the excess costs.

Of course, many patients have commercial insurance to cover this part of the cost.

For uninsured patients,
The cost of one dialysis treatment will reach $400. If calculated based on three times a week, twelve times a month, and 144 times a year, the annual cost for dialysis patients in the United States will be close to $6.

The scariest thing is that if it is an unplanned, emergency dialysis, the cost will be as high as thousands of dollars!

"Zhang, you're right to listen to me. Just sell it at $500 per injection. I'm confident that I can convince Medicare and commercial insurance to include our Kidney Toxin Clearing Dialysis Injection in their insurance coverage!"

"Don't worry, I will make it popular all over America!"

Under Friedman's persuasion, Zhang Yang set the selling price in the United States at US$500 per injection, while the agency price to Novartis was US$300 per injection, equivalent to RMB 2100.

After determining the selling price in their respective markets, the two immediately flew back to China to begin promotion, and also began to promote the inclusion of "Kidney Toxin Clearing" into their respective medical insurance systems.

After all, the "Kidney Toxin Clearing Dialysis Injection" is not like other drugs. If you really want to promote it, you must bind it to medical insurance.

Just as GlaxoSmithKline and Novartis began to vigorously promote the upcoming launch of "Kidney Toxin Clearing" in the UK and the US, the domestic medical insurance bureau also noticed the news that "Kidney Toxin Clearing Dialysis Needle" had passed the clinical trial.

Beijing, China Medical Insurance Bureau Building.

A discussion on Qingshan Pharmaceutical's "Kidney Toxin Clearing Dialysis Needle" is coming to an end, and Liu Weiguo, director of the procurement department, is making his final closing remarks.

"Everyone has worked hard this afternoon, but the good news is that we have finally discussed the bottom price of Qingshan Pharmaceutical's 'Kidney Toxin Clearing Dialysis Needle'."

"I won't repeat the confidentiality rules. Before the negotiations with Qingshan Pharmaceutical are completed, no one can disclose today's discussion. Do you understand?"

"clear."

"Okay, let's break up the meeting."

The dozen or so comrades who participated in the discussion breathed a sigh of relief.

Every time Qingshan Pharmaceutical launches a new drug, the General Administration will discuss the price of the new drug to be included in medical insurance some time in advance.

There is no way. Every time Qingshan Pharmaceutical’s new drug has an unparalleled therapeutic effect, it is urgently needed by patients.

If it is too expensive, medical insurance cannot afford it. If it is too cheap, Qingshan Pharmaceutical will definitely not be willing to join the medical insurance. So this is a difficult job.

Fortunately, Qingshan Pharmaceutical’s “Kidney Toxin Clearing Dialysis Needle” is not unique this time, so at least there is a reference, and the discussion went smoothly.

Liu Weiguo also rubbed his temples and breathed a sigh of relief.

He returned to the office with the documents, but before he sat down, the office phone rang.

"Weiguo, come to my office."

"Okay, Director Wei."

Liu Weiguo quickly put down the documents and went to Director Wei Ming's office. He had already vaguely guessed why Director Wei was looking for him.

really.

"Weiguo, I heard that you were discussing the medical insurance price of Qingshan Pharmaceutical's 'Kidney Toxin Clearing Dialysis Needle' this afternoon? Is the discussion over?"

Liu Weiguo nodded. Reporting work to Director Wei certainly wasn’t considered a leak.

"Yes, Director Wei, we already have a preliminary psychological price. Now it depends on when Qingshan Pharmaceutical will propose to negotiate with us."

"Well, the result of your discussion...what is our psychological price?"

……

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(End of this chapter)