Naruto: With maxed-out affection, I am invincible in the ninja world.

Although he felt a little embarrassed and awkward praising himself, he maintained his glorious image in front of the students.

What does it mean that Shikamaru, Shikaku's son, is secretly laughing in the back row?

Haneda, remembering that this guy would be Naruto's future strategist, revealed a sinister smile.

He won't be laughing anymore after he graduates.

Kakashi used the Flying Thunder God Technique to teleport back to Fugaku's house. Sitting on the sofa, he grumbled:

"You've been back for so long, Haneda? Aren't you only supposed to pick them up and drop them off at school?"

Haneda smiled and said, "Naruto and Sasuke are late. I wanted to see their reaction, but unfortunately, they don't have the composure of Obito back then."

When Obito was mentioned, a hint of nostalgia and pain flashed in Kakashi's eyes.

To conceal his pain, he quickly brought up the important matter with Shisui:

"Haneda is going to help you and Itachi transplant Hashirama's cells to completely resolve the eye problems caused by the depletion of their eye power."

"Will there be any danger?" Itachi asked worriedly.

Haneda explained to Kakashi:

"No, I'll be watching from the side."

"In special circumstances, I can use my pupil technique to forcibly absorb the transplanted first-generation cells."

Upon hearing that Haneda had prepared a complete plan, Shisui looked at Haneda gratefully.

Compared to the inherently evil Danzo, Haneda, who had no special relationship with him, took better care of him.

Whether it's making him Kakashi's direct subordinate, or considering his eyes and pupil power...

Unlike Shisui, Itachi did not use his eye techniques as frequently; his eye power was well preserved, and he had no worries about his eyes.

But when he heard that Haneda had taken the initiative to help Shisui repair his eyes, he was very grateful to Haneda.

However, there was one question that Itachi couldn't help but voice:

"Has Father already received the first-generation cell transplant? Why didn't you invite him?"

Upon hearing why Fugaku didn't transplant the First Hokage's cells, Haneda looked at Itachi with a somewhat complicated expression.

He promised Fugaku that he wouldn't reveal the real reason, so he made up an excuse:

"When transplanting first-generation cells, a human face may grow at the transplant site. If Mikoto sees the pattern on Fugaku's body, she will feel uncomfortable."

"You know how much Brother Fugaku loves Sister Mikoto, just like he loves you."

Itachi knew that women are naturally fond of beauty, and having a human face on their body was indeed somewhat repulsive.

Seeing that Itachi didn't press the matter, Haneda breathed a sigh of relief and said casually:

"Let's go, I've already notified the good guys to prepare for the transplantation of the first-generation cells."

"The location is the Root Base beneath the Forest of Death; you should be very familiar with that place."

Haneda, with Itachi by his side, and Kakashi, with Shisui by his side, used the Flying Thunder God Technique to instantly teleport to Orochimaru's laboratory at Root.

When Orochimaru, with his long black hair, golden snake eyes, and pale skin, appeared, Itachi and Shisui instantly stood in front of Haneda and Kakashi, assuming a fighting stance.

"Orochimaru, an S-rank rogue ninja from Konoha!"

…………

Chapter 284 Transplantation of Primary Cells

“He’s the doctor I invited to take charge of this cell transplant, so don’t be nervous,” Haneda explained from the side.

Upon hearing this, Itachi and Shisui looked puzzled and confused, but trusting Haneda, they relaxed their guard.

Orochimaru looked into Itachi and Shisui's eyes and couldn't help but lick his lips.

He had been very curious about the Uchiha's eyes for many years.

That's something that can suppress the first generation of cells, and might even uncover a hidden history.

Although Orochimaru wasn't particularly interested in history, it did involve the legendary Ninja Cult.

"It's best to stay relaxed and in a good mood before transplanting primary cells."

"Although the process will be painful and long, if you can persevere, it will be a test of your will."

Orochimaru explained as he organized and inspected the experimental equipment.

This is the first study on the suppressive power of the Mangekyou Sharingan on the First Hokage's cells.

Based on the performances of Madara Uchiha and Hashirama Senju during the Warring States period, the Mangekyou Sharingan and the First Hokage's cells should be roughly equal.

This undoubtedly increases the success rate of transplanting primary cells.

With his familiarity with the first generation of cells, Orochimaru was very confident that the transplant would be successful.

Seeing that Orochimaru had made thorough preparations, Haneda gave the instructions:

"Let's take it one at a time. Once the first-generation cells survive the first round of bloodline rejection, the rest will be relatively easier."

"Shisui, you go first."

"Yes, Hokage-sama."

Orochimaru prepared two experimental beds, one on each side, very close together, only one meter apart.

Zhishui habitually chose the right side of the position.

His right eye was recovered by Haneda, and he instinctively felt that his right eye would bring him good luck.

Once Shisui was lying down, Orochimaru took out a thick test tube with an unusually long and thin needle.

Upon seeing the syringe, Shisui, lying on the bed, recalled painful memories and felt an instinctive sense of terror.

Haneda and Itachi, standing to the side, couldn't help but swallow hard.

This injection alone could scare a child to tears, right? Even adults would find it creepy.

"These are my first-generation cells, processed using special methods."

"The effects after transplantation may be much weaker, but his irritability will be lower, and the probability of successful transplantation will be higher."

"I have not studied the Mangekyou Sharingan, so I don't know how strong its suppressive power against the First Hokage's cells is."

Orochimaru's voice, cold yet extremely calm, came through, a voice that reminded him of his experiences cooperating with the Root ninjas.

Although they lack emotions, their mission completion rate is higher.

This reassured Shisui.

Haneda reassured her, "Relax, even if your transplant fails, I can save your life."

"Even if you lose that power, it will be alright. I will bear the burden of everything for the Uchiha and Konoha."

Shisui looked at Haneda's Mangekyou Sharingan.

The sun pattern exudes an eerie, evil, and dark aura, yet this aura warms his heart.

Shisui secretly made up his mind that he must succeed in transplanting the first-generation cells.

He wanted to help Lord Haneda take on more of the responsibilities of Hokage and leader.

As one of the people in charge of purging the remnants of the daimyo's faction, Shisui was well aware of the prejudice and hatred that the people of the new Land of Fire held towards Lord Haneda.

He wanted to use the power of the gods to change their wrong beliefs.

The syringe was injected into the stopped chest, and soon a pale human face appeared at the injection site.

Orochimaru calmly immobilized Shisui's arm and thigh, and inserted a catheter into the vein in Shisui's arm.

"This is a suppressive poison; it's something I traded from Scorpion."

"It can have a significant suppressive effect on primary cells."

"It has to be said that he developed a wide variety of poisons, and you can always get something useful from him that is both useless and useful."

Orochimaru didn't mention that the poison had undergone special processing, and anyway, Haneda and the others wouldn't understand anyway.

As specially treated poison was injected into Shisui's body, the pale face on Shisui's chest began to fade, and the pale area also began to compress.

Zhishui's facial pain has been relieved considerably.

Orochimaru carefully recorded the data transmitted from the experimental equipment.

According to his earlier research, the success rate of transplanting first-generation cells is actually higher when the patient is younger.

The success rate of Shisui integrating into the First Hokage's cells depends entirely on the suppressive power of the Mangekyou Sharingan.

Suddenly, the previously calm heart rate fluctuations began to change drastically, and the most severe moment of rejection had arrived.

Orochimaru stared intently at the changes in heart rate fluctuations.

Previous studies have shown that more stable cells have longer survival times, less rejection, and higher success rates.

However, Shisui's heart rate fluctuated so drastically that Orochimaru would have already pronounced him dead if it weren't for the Mangekyou Sharingan.

Noticing Orochimaru's expression becoming very serious and Shisui's pain intensifying, Haneda and Itachi realized that Shisui was in grave danger!

Experiments involving transplanting primary cells could fail at any time!