After being fired, I became the light of medicine

Chapter 95 Can elafovir be used for liver cirrhosis?

Chapter 95 Can elafovir be used for liver cirrhosis? (asking for monthly votes)
I don’t know how long he watched in the group, Liang Guangming finally put down his phone and lay back on the hospital bed.

Gradually, he thought of his daughter and his wife...

Perhaps it was because he couldn't sleep at all these few nights, and before he knew it, Liang Guangming, who was lying on the bed, gradually fell asleep.

He didn't know how much time had passed before he was awakened by a rustling sound from the bed next door.

Liang Guangming was in bed number 14, and bed number 15 next to him was previously vacant...

He looked curiously and saw that the patient who had just been admitted to the hospital had a thin face and looked to be about 50 years old. He was lying quietly on the bed, and one could tell at a glance that his condition was serious.

The accompanying family member was about thirty years old and should be the patient's son.

After the patient's son packed up his belongings, he couldn't help but ask curiously during his break:

"Little brother, what's wrong with your father?"

"Liver cirrhosis, decompensation stage."

Decompensation period...

Liang Guangming's heart trembled for no reason.

In fact, after being diagnosed with early-stage cirrhosis these days, he has a deeper understanding of cirrhosis.

Simply put, people often distinguish cirrhosis into early cirrhosis and late cirrhosis, while from a professional perspective, there are two stages: compensated stage and decompensated stage.

Early cirrhosis is equal to the compensated stage of cirrhosis.

Advanced liver cirrhosis is equal to the decompensated stage of liver cirrhosis.

The symptoms of compensated cirrhosis are not too obvious. Just like him, the transaminase level is slightly elevated, and there are occasional fatigue, loss of appetite, upper abdominal pain, etc.

At this time, the compensatory function of the liver is still basically normal, but once it reaches the decompensation stage, the liver function is seriously damaged, not only will the patient have no appetite, fatigue, and vomiting.

The most serious ones are patients with decompensated cirrhosis who are often prone to serious complications such as ascites and esophageal varices.

These complications can easily lead to life-threatening situations.

Once this point is reached, life almost enters the countdown.

Thinking of this, Liang Guangming suddenly looked at the patient lying on the bed with some fear, as if he saw his own future.

After a moment, he didn't want to continue this topic:

"From your accent, aren't you from Chengdu?"

"Well, my name is Liu Haoran, you can call me Xiao Liu, we are from Jie City, Guangdong Province."

"We went to Guangzhou for a checkup, and the doctors there told us to let nature take its course, but my father is only 52 years old, and we don't want to give up just like that."

"It just so happens that a relative of ours who is a doctor suggested that we try this hospital."

"Ah? Come and try it here?"

Liang Guangming felt a little strange. Chengdu Third People's Hospital was not very famous in the liver disease department. After coming all the way from Guangdong Province, he should at least go to West China Hospital, right?
Liu Haoran seemed to see the doubt in Liang Guangming's heart and explained:

"My relative who is a doctor told us that we can come here and try using 'Acofenprofovir'..."

"'Afovir'? Isn't this a cure for hepatitis B?"

"Yes."

Liu Haoran nodded and continued, "In 1984, when he was 12 years old, the school conducted a comprehensive hepatitis B test and found that he was infected with hepatitis B. This year has been more than 40 years."

"His liver cirrhosis is caused by the long-term failure to control the hepatitis B virus, which has now developed into the decompensated stage."

"My relative's doctor told us that this hospital is a clinical trial hospital for 'Ekofovir' and has a lot of experience in the clinical use of 'Ekofovir'...

He wanted us to see if we could cure my dad's hepatitis B by using 'Afovir' and thus slow down the progression of the disease."

"certainly,"

He paused, glanced at the patient sleeping on the bed, and whispered:
"We don't want to be cured, we just hope to live longer."

Liang Guangming's eyes were startled, and suddenly a strong hope burst out in his eyes.

indeed.

It's the same for him. Hepatitis B is the cause of his liver cirrhosis.

If I take "Afovir" to completely eliminate the hepatitis B virus, does that mean that cirrhosis will not develop again? !
Suddenly, Liang Guangming became very excited, but the next second,
He thought of the extremely strong side effects and cytotoxicity of "Afovir"!
"Acofenprofovir" is targeted at common hepatitis B patients. Even if these hepatitis B patients have some liver damage after taking it, they can still recover thanks to the powerful regenerative function of the liver.

What about those patients who already have cirrhosis of the liver?
It might even lead to more serious consequences!

and.

Now that I have developed liver cirrhosis, will it be useful to take "Afovir"?

His heart was beating fast.

Fortunately, Liu Haoran's words gave him a new plan. He decided to ask his attending physician for advice when he has time!
Liang Guangming's attending physician is Director Chen Wen. After asking him early the next morning, Director Chen Wen did not give a clear answer.

“Currently, ‘Avofafovir’ has just been launched on the market, and no clinical trials have been conducted on patients with liver cirrhosis;
Whether it can be used in patients with cirrhosis and whether it will have a significant prognostic effect after use, there is currently no clinical precedent, and we still need to consider it carefully."

He could also understand Director Chen Wen's concerns.

but,

After several days of hospitalization, he clearly felt that the number of inpatients in the Hepatology Department of Chengdu Third People's Hospital was increasing, and the vast majority of them were patients with cirrhosis.

Most people want to try using "Afovir" to treat liver cirrhosis.

As more and more patients raised their demands, Director Chen Wen convened a department meeting with the Department of Gastroenterology and the Department of Hepatobiliary Surgery.

"Let me briefly talk about the current situation. Currently, 95% of the patients with cirrhosis admitted to our department are caused by the hepatitis B virus."

"Although these patients have already started antiviral treatment, we all know that even diphenhydramine can only inhibit the replication of hepatitis B virus, but cannot completely kill it. This results in a small amount of hepatitis B virus still attacking the liver in these patients with cirrhosis."

"If it is an ordinary hepatitis B patient, they can barely achieve a delicate balance through liver regeneration, but the liver cell regeneration ability of patients with cirrhosis is extremely weak. Even a small amount of hepatitis B virus will inevitably cause further damage to the liver in the long run!"

"'Avofovir' can indeed kill all hepatitis B viruses, but the side effect is that it causes more liver damage."

"The question now is: should we take the risk of using icofenac in patients with cirrhosis?"

"Will it be beneficial to prolong his life in the future? Or will it cause further damage and accelerate the deterioration of his condition?"

……

PS: Thanks to the book friend 150617041032603 for the 200-coin reward

It will be on the shelves on Wednesday, the time is confirmed, and there will be a lot of updates once it’s on the shelves. I hope everyone can support it then!
Asking for a monthly ticket!
(End of this chapter)

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