After being fired, I became the light of medicine

Chapter 234 New drug - Ibetaxol!
"name?"

"Xia Xue."

"body temperature?"

"39.8 degrees... Uh, the patient's family just said that the patient had a fever since last night. He took ibuprofen capsules three hours ago to reduce the fever, but it didn't work. Now the temperature has risen again."

"Ah."

In the emergency room of the Hematology Department of Chengdu Third People's Hospital.

A middle-aged man looked at Xia Xue lying on the emergency table and asked a doctor next to him.

"What about the blood pressure and electrocardiogram results?"

"Blood pressure is 110/70, normal; electrocardiogram results are normal."

The middle-aged man once again quickly recorded on the paper record sheet.

"Also, Mr. Wei, this patient received his first bone marrow stem cell transplant five years ago, and he underwent a second bone marrow transplant about three months ago because of a relapse of leukemia."

"The operation was quite successful, but in the second month after the operation, which was last month, an acute rejection reaction occurred!"

"After the patient came to the hospital for simple treatment, the patient and his family eventually chose to give up treatment."

"When they were discharged from the hospital, I prescribed Qingshan Avatrombopag tablets and cyclosporine, an anti-rejection drug, to them. The patients should have been taking the medications normally over the past month."

"It seems that the drugs are no longer able to suppress the rejection reaction, causing the transplanted 'bone marrow stem cells' to completely lose their function and the patient's leukemia to relapse... The leukemia cancer cells are multiplying and spreading again."

The middle-aged man asking the question was Wei Tian, ​​and the doctor standing next to him was Director Hu.

After learning that Qingshan Pharmaceutical had developed a drug that could treat acute myeloid leukemia and was about to conduct clinical trials, Director Hu thought of Xia Xue first.

Upon learning that Xia Xue was still alive but in a very critical situation, he hurriedly contacted Zhang Yang through his personal connections, hoping that Zhang Yang could make some arrangements and help give Xia Xue the medicine immediately.

As we all know, clinical trials of innovative drugs are conducted in batches, which involve probabilistic issues such as "double-blind testing", and the experimental drugs may not actually be used.

Zhang Yang took the situation very seriously after learning about it, and immediately asked Wei Tian to come in person to understand the specific situation and make individual arrangements for the patient's medication.

As the person in charge of the "BXB01" drug project, Wei Tian was naturally not cautious and was extremely alert as the first human clinical trial of "BXB01" was being conducted on leukemia patients with such serious conditions!

"What about the blood picture? Director Hu, what is the blood picture now?"

“血象检查刚出来，白细胞计数已经达到了231×10/L，一般正常成年人是是4.0~10.0×10/L，现在已经超出了正常23倍！”

"At the same time, the patient's hemoglobin and platelet counts also fell below 40% of the normal value, and this was despite continuing to take Qingshan Afa!"

"Taken together, the blood picture is completely consistent with the high-risk condition of late-stage acute leukemia."

Wei Tian exhaled lightly and nodded.

However, he did not end the questioning. He glanced at the record sheet in his hand and continued:
"The last item, what are the results of the color Doppler ultrasound and PET-CT?"

Director Hu showed no sign of impatience. He quickly flipped through the inspection report in his hand and said quickly:
"The results of the color Doppler ultrasound showed that the patient had obvious liver and spleen enlargement, which are also typical symptoms of late-stage leukemia."

"I just had a PET-CT (to check the distribution of cancer cells in the body) done. I have urged the radiology department to get the results as soon as possible, but I don't think the results will be very good."

As he spoke, he paused and looked at Wei Tian:

"I estimate that the leukemia cancer cells have spread throughout the body, but fortunately, leukemia does not metastasize in the traditional sense like traditional solid tumors."

"Leukemia cancer cells do attack organs such as the liver, lymph nodes, and spleen, but it's not too late to take medication now!"

"Ok!"

Wei Tian nodded heavily, then put away the record sheet in his hand.

He glanced at Xia Xue, who was lying weakly on the emergency table, and said no more:

"Director, I have understood and recorded it!"

"This patient's condition completely meets the requirements for our new drug's clinical trial patients. Let's not waste any time, shall we? Let's use the drug immediately after her family members sign the clinical trial consent form!"

"it is good."

Director Hu's face lit up with joy, and he finally breathed a sigh of relief:
"Boss Wei, I'll go and notify the patient's family to sign... By the way, shall I take you to the meeting room first?"

"No need, Director. I'll go to the conference room and wait for you!"

"also!"

……

As soon as the voice fell, Director Hu took the lead and walked to the ward where Xia Xue was placed when she was admitted to the hospital, while Wei Tian quickly walked to a small meeting room next to the corridor of the department.

This time he was accompanied by Dr. Zhou from the first project team and another staff member, who had been waiting in the conference room for a while.

Two minutes later, Director Hu personally brought Lao Xia into the conference room.

Looking at the three people sitting at the conference table in front of him, Old Xia had a dull expression and his mind was completely confused.

In fact, ever since he received Director Hu’s call and came to the hospital, he has been completely confused.

His daughter was pushed into the emergency room. He didn't know what he should do next or what he could do. He could only wait quietly for Director Hu's arrangements.

"Old Xia, don't just stand there, these people are the CEOs of Qingshan Pharmaceutical, and they are here specifically for your daughter's matter!"

"It has been confirmed that your daughter is in good condition and can use the medicine. All you need to do next is sign and record a video before you can use Qingshan Pharmaceutical's medicine!"

Seeing that Old Xia looked confused, Director Hu hurriedly spoke up to remind him.

After a moment, the panic-stricken Old Xia finally recovered. His eyes instantly fell on Wei Tian who was sitting in the middle, and he said hurriedly:
"Hello, all the bosses! Hello! Please save my daughter!"

Seeing this, Wei Tian stood up hurriedly and said soothingly:

"Brother, don't worry, you are the family member of the patient Xia Xue, right?"

"Ok!"

Old Xia's mood calmed down a little.

Seeing this, Wei Tian continued:
"That's good. Now there are a few main issues that I must clarify with you in advance!"

"Because your daughter's condition is rather special and now in a very dangerous state, we can no longer allow her to participate in the normal clinical trial process. We can only use emergency medication to conduct drug experiments on her alone!"

"Therefore, before using the medicine, we need to record the entire process in audio and video and sign it to ensure that you are aware of the risk!"

Only then did Old Xia notice that a small DV camera had been set up on the conference table next to him, with the camera facing him.

But he quickly reacted and nodded repeatedly:
"Boss, I can accept it, I am willing!"

"Okay! Please take a seat first. If there is no problem, we will start now."

"it is good!"

As soon as the words fell, everything was ready, and Wei Tian nodded to the staff next to him.

Two seconds later, the staff member made an OK gesture, indicating that the camera mode had been turned on.

Wei Tian's expression suddenly became serious, and his tone became solemn.

He looked at Lao Xia and said in a low voice:

"Excuse me, are you the direct relative of the subject Xia Xue?" "Yes!"

"May I ask what your relationship is?"

"My subject Xia Xue's father is now in critical condition and cannot sign the informed consent form, so I will sign on his behalf!"

"it is good!"

Wei Tian breathed a sigh of relief, but soon, his expression became more serious and solemn.

"Okay, father of the test subject Xia Xue, I will now inform you verbally and in writing about the relevant information of the clinical trial drug and the possible risks you may encounter!"

"The subject, Xia Xue, will be taking the latest drug developed by our company, Qingshan Pharmaceutical, for the treatment of 'acute myeloid leukemia'. The full name of the drug is Ibetuzumab, abbreviated as 'Ibetuzumab'."

"This drug is an antigen-targeted drug that our company has developed over seven years and invested a huge amount of research funds to effectively kill 'acute myeloid leukemia' cancer cells."

"In our more than 1000 complete animal tests, the drug ultimately achieved an overall effective killing rate of 79-82% in animals."

"but!"

"In animal experiments, many adverse reactions also occurred, such as some normal white blood cells and red blood cells being mistakenly identified and killed by drug ingredients, resulting in a decrease in the number of white blood cells in the animals and causing bleeding."

"For example, if drug ingredients remain in the body for a long time, normal hematopoietic stem cells will eventually be affected, causing them to lose their hematopoietic function or become functionally incomplete!"

"Even in the most extreme cases, it may cause massive depletion of white blood cells and red blood cells at the same time, leading to the direct death of the animal receptor!"

"At the same time, these are only the known risks in animal testing, and there are many more unknown risks that are not yet known!"

"Excuse me, are you fully aware of the risks involved and are you willing to bear all the consequences of taking the medicine?"

79%~82% effective killing rate!

Old Xia was stunned, his mind was filled with the effective killing rate of 79% to 82%!

At this moment, my daughter is already on the verge of death, so why should I worry about the risks of drugs!
"I do, I do! I'll sign it right now!"

"If anything goes wrong, I will never come to you!"

Old Xia signed his name on the informed consent form without hesitation, and this moment was recorded entirely by the DV.

A few seconds later, the staff member on the side stopped filming, checked once and found that there was no problem, and Wei Tian breathed a sigh of relief.

Soon, his eyes fell on Lao Xia's face again.

He could understand Lao Xia's feelings at the moment, but even so he had to thank Lao Xia for his contribution to the clinical trials of new drugs.

solemnly said:
"Brother Xia, thank you for your support for our Qingshan Pharmaceutical's new drug! We will give your daughter the drug right away!"

"Of course, you don't have to worry too much. Although our new drug has certain drug risks, I think it should still have a high probability of producing a certain therapeutic effect!"

Old Xia's expression also relaxed, and even a hint of spirit returned to his eyes.

He nodded heavily, and at this moment, Wei Tian continued:
"Oh, there's one more thing I want to tell you!"

"Since you are willing to participate in the clinical trial of our new leukemia drug 'Ibetuzumab', all the treatment costs of your daughter in the hospital will be borne by us!"

"This! Are you responsible for it?!"

Old Xia was stunned, unable to believe it!

You know, even though he brought his daughter to the hospital, the issue of medical expenses was weighing on his mind and making him feel suffocated!
"Ok!"

"At the same time, after completing the six-month clinical trial, we will give you a compensation of approximately 3.5 yuan!"

"Again, thank you for your contribution to our new drug 'Ibetumumab'."

Fully cover the cost of treatment.

Another 3.5 yuan is required!

Old Xia was silent.

A moment later, he suddenly knelt down, his originally dry eyes already filled with tears.

"Boss, not only are you treating us for free, you're even giving us money!"

"How can I feel at ease?"

"You are all good people, you are really the best and best company in the world!"

The sudden situation caught Wei Tian off guard, but fortunately Director Hu had seen it many times.

He was the first to react and stepped forward to persuade Old Xia:

"Old Xia, get up. Qingshan Pharmaceutical has always been a pharmaceutical company for the people and has always been thinking about ordinary patients like us."

Wei Tian also hurriedly stepped forward and helped Old Xia up:

"Brother Xia, you don't have to do this."

"Just like our President Zhang Yang said, developing drugs to treat various diseases is our job and what we should do!"

There was a moment of noise in the small meeting room. Dr. Zhou quietly looked at Old Xia, who was kneeling on the ground with tears in his eyes, and listened to his heartfelt thanks. He suddenly felt that everything was worth it!

Is there anything in the world that could be more meaningful than saving lives?

……

After signing the informed consent form for the clinical trial, Dr. Zhou handed over the "ibacterium tuzumab" that he had brought personally but had not yet provided to the clinical trial center to Director Hu.

"Ibetuzumab" is also a targeted drug. It is an injectable drug and only requires one injection a week.

At the same time, "Ibetuzumab" cannot currently cure "acute leukemia", and even the results of animal experiments show that it can only eliminate about 80% of leukemia cancer cells in the body.

This time, Director Hu planned to stop taking all other drugs for Xia Xue and start a clinical trial using only "ibacterium vaccinium".

As the world's first drug for treating acute leukemia, "Ibetuzumab", was injected into Xia Xue's body, Xia Xue also began to accept more accurate and precise data records.

Four hours after the injection, Xia Xue's condition began to improve.

The high temperature of 40 degrees began to drop to 39.5 degrees for the first time with the intervention of non-antipyretic drugs.

As the temperature dropped, Xia Xue's mental state began to improve.

Eight hours after the injection, Xia Xue's body temperature dropped to 8 degrees.

The first blood test results are out.

The previously astonishing white blood cell count of 231×10/L dropped to 170×10/L.

After 24 hours, Xia Xue's body temperature dropped to 38.5 degrees and her mental state improved completely.

The white blood cell count also dropped to 120×10/L, which is only 12 times higher than the normal value!
At the same time, important leukemia indicators such as red blood cells and hemoglobin data began to rise steadily!
A large amount of monitoring data was transmitted to Director Hu, who then shared it with Wei Tian and Dr. Zhou. In just one day, everyone realized that—

Tsingshan Pharmaceutical’s latest drug, “Ibetuzumab” for the treatment of acute leukemia, is really effective on the human body!

At this time, Tsingshan Pharmaceutical finally officially announced that "Ibetuzumab" had passed the ethical review and would soon enter the hospital for clinical trials!

As soon as the news came out, the Internet exploded!
(End of this chapter)