Chapter 145: Fame! (Subscribe)
The sales of "Kidney Toxin Clearing Dialysis Replacement Needle" quickly increased in foreign markets. Westerners value freedom and are more receptive to new things, so the promotion was extremely smooth.

Although the acceptance rate among domestic patients is low, and some patients are worried about the treatment effects and side effects, many patients have begun to try using the "Kidney Toxin Clearing Dialysis Needle" under the advice of doctors.

In just one month, 103000 injections of "Shenduqing" were prescribed in major domestic hospitals, with sales exceeding million yuan!

It should be noted that the current global hemodialysis market consumables sales are US$140 billion, of which the US market accounts for the largest share, reaching 29%, totaling US$40.6 billion.

The European Union came second, with approximately US$35 billion, accounting for 25%.

China is the world's third largest hemodialysis market, with annual sales reaching US$29 billion, accounting for 20.5% of global sales.

29 billion US dollars is equivalent to 203 billion RMB, which translates to monthly hemodialysis market sales of 16.9 billion RMB.

The sales of Qingshan Pharmaceutical's "Kidney Du Qing Dialysis Replacement Needle" exceeded 5.9 million yuan within one month after its launch, which means that the market sales share of "Kidney Du Qing" in the domestic "hemodialysis market" reached % in just one month!

The situation abroad is similar.

Since GlaxoSmithKline has not yet fully expanded its sales in the European market, the monthly sales data sent back by Novartis in the United States is very encouraging.

In one month, major hospitals across the United States prescribed a total of 126000 "Kidney Toxin Clearing Dialysis Injections", at a price of US$500 per injection, the sales amount reached US$6300 million.

The total annual sales of the hemodialysis market in the United States is 40 billion US dollars, about 3.3 million per month.
The market penetration rate of “Kidney Toxin Clearing Dialysis Needle” reached 2% in the first month of sales in the United States!

Zhang Yang is very satisfied with this data. Based on the first month's sales data, he is confident that the domestic market share will increase to 25-30% within half a year!

The overseas market should be able to achieve a market share of about 15% within half a year. By then, the global market share of "Shenduqing" may reach 20%!

Just when Zhang Yang asked Lotus Pharmaceuticals to increase its production capacity, he didn't know that Lin Xiang, director of the Nephrology Department of Chengdu Third People's Hospital, had already begun trying to use the "Kidney Toxin Clearing Dialysis Needle" on non-dialysis patients.

That is, patients like the young Luo Hao, who have not fully met the criteria for uremia but are already in stage 4 kidney disease and need dialysis.

At 9 p.m. on September 10, the door of the nephrology department's inpatient classroom was closed.

Two chief physicians, four deputy chief physicians, seven attending physicians and three resident physicians of the Department of Nephrology were all present.

Director Lin Xiang stood on the podium at the top of the conference room. Behind him was a teaching screen that displayed the case content being discussed today.

And below, all the nephrology doctors, regardless of their position, looked at the screen seriously and took notes in their notebooks from time to time.

“In the past month, we have tried using the ‘Kidney Toxin Clearing Dialysis Needle’ on three ‘Stage IV Kidney Disease’ patients;
The glomerular filtration rates of these three patients were 25%, 28%, and 24% respectively, which did not meet the requirement of uremia, which is a filtration rate of less than 15%!"

"According to the treatment plan in the National Chronic Kidney Disease Treatment Guidelines, the conventional plan is to first use diuretics to eliminate the water in the body due to edema, and then take hormones and kidney disease drugs to control kidney inflammation while slowly excreting toxins from the human blood, thereby achieving the goal of lowering creatinine!"

"but!"

"We are all experienced clinicians, and we all know that it is easy to expel water after using diuretics, but it is actually difficult to reduce toxins in the blood and the patient's creatinine."

"For patients who are lucky, taking medication can extend the time it takes to develop uremia by one or two years. For patients who are unlucky, most of them will have their glomerular filtration rate drop below 15% after half a year, turning into uremia, and then they will have to undergo dialysis!"

The doctors nodded in agreement.

When it comes to "Kidney Stage IV", the glomerular filtration rate is only 25%, which makes it impossible to completely excrete toxins from the body.

Whether taking hormonal drugs or drugs to protect the kidneys and lower creatinine, they can only relieve kidney inflammation and protect the kidneys, but they cannot help the kidneys complete their function of filtering toxins.

If the kidneys continue to work without rest and are slightly damaged again, 99% of patients will develop uremia.

It can be said that once you reach "kidney stage 4", you basically just need to take some medicine, do your best, and leave the rest to fate.

"so."

Lin Xiang continued:

"I tried using the 'Kidney Toxin Clearing Dialysis Needle' on three young patients with 'Stage IV Kidney Disease'. After one month of continuous follow-up, the results were surprising."

"The water in the three patients' bodies was rapidly discharged, and their blood creatinine also dropped rapidly. After the first injection, the creatinine of the three patients dropped to around 100, which means that the toxins in the body have been quickly discharged."

"What is most surprising is that perhaps the kidneys were effectively rested. After using 'Kidney Toxin Clearing' for one month, the three patients' glomerular filtration rate did not continue to decline, but stabilized at 25% or even slightly increased!

At the same time, important kidney indicators such as creatinine, urea, and uric acid all dropped significantly and are close to normal!"

As soon as he finished speaking, all the doctors present were stunned for a moment. After seeing the one-month tracking data displayed by Lin Xiang on the screen, all the doctors were shocked!
"This... is this without dialysis? Is this the effect achieved by just using the 'Kidney Toxin Clearing Dialysis Needle'?"

"This makes the renal function indicators of patients with 'Kidney Stage IV' almost back to normal?!"

Listening to a doctor's surprised question, Lin Xiang nodded and confirmed:

"That's right, I didn't expect this result!"

"At the beginning, I wanted to quickly excrete toxins and water from the patient's body so as to better protect the kidneys during treatment."

"After I gave the patient two injections of 'Kidney Toxin Clearing Dialysis Needle', according to the medication guide, he needed to undergo dialysis, but he did not meet the criteria for dialysis."

"I tried the third injection and the effect was still very good!"

"I guess the 'Kidney Toxin Clearing Dialysis Injection' seems to help the kidneys complete 80% of the work, while the patient's kidneys, which only have 25% function, do the remaining 20% ​​of toxin removal work. There seems to be a delicate balance between the two."

Kidney Toxin Clearer completes 80% of the work!
A delicate balance!
This explanation caused all the doctors present to brainstorm. After a moment, a deputy chief doctor suddenly stood up and said excitedly:
"Director Lin, I think your guess is entirely possible!"

"According to drug information provided by Qingshan Pharmaceutical, the 'Kidney Toxin Clearing Dialysis Needle' can achieve an 80% toxin removal effect, and is particularly effective against small molecule toxins."

"Why do they require hemodialysis after two injections? It's because 'Kidney Toxin Clearing' can't remove large molecule toxins!"

"Although patients with 'stage 25 kidneys' only have a filtration rate of about %, compared to patients with uremia, they can still function!"

"In this case, it is entirely possible that 'Kidney Toxin Clear' first filtered out a large number of small-molecule toxins like a nanny, and the remaining 20% ​​of large-molecule toxins were filtered out by the patient's kidneys!"

Like a nanny!
This description is very apt!

"Kidney Toxin Clear" acts as a nanny to do the big work, and the damaged kidneys to do the small work. When you are done, you can have a good rest! All the doctors in the conference room visualized the effect of "Kidney Toxin Clear". Even Lin Xiang was slightly startled, and then smiled:

"It's just like what Dr. Gao said, Shenduqing plays the role of 'kidney nanny'!"

"So next, I plan to try to apply 'Kidney Toxin Clearing' to more patients with 'Stage IV Kidney Disease' or even 'Stage III Kidney Disease'!"

"Everyone knows that 'stage 30 kidney disease' is a glomerular filtration rate of 59%-%. Currently, there is no effective drug in the entire medical community that can control the development of stage kidney disease. Many patients have watched stage kidney disease develop into stage and finally develop into uremia!"

"If the 'Kidney Du Qing Dialysis Needle' can be used in advance on patients with 'stage 3 kidney disease', with the help of 'Kidney Du Qing' as a nanny, will the patient's kidneys get a better rest, thereby controlling the 'stage 3 kidney disease' from getting worse, or delaying the progression?!"

"Totally possible!"

Lin Xiang's hypothesis instantly excited all the doctors!
Clinically, the reason why "Stage III Kidney Disease" continues to worsen and is difficult to control is: even if you take medicine every day to protect your kidneys and suppress inflammation, your kidneys still have to work all the time, and a glomerular filtration rate of 50% leaves almost no time for the kidneys to rest!

How is it possible not to suffer sustained injuries under high-intensity work?
Now if we have "Kidney Toxin Clearing" as a nanny to help, the kidneys only need to do 20% of the work, then there can still be problems? !
"Director Lin, I think this clinical topic is very good. I request that a departmental team be set up immediately to start clinical work!"

"I agree. According to this idea, the 'Kidney Toxin Clearing Dialysis Needle' may become a routine treatment for 'stage three and four kidney disease'!"

"Yes, we should start right away. If the patient can stabilize his condition by using 'Kidney Du Qing' for a long time, it is better than worsening to the point where he needs dialysis, right?"

"That's right. If we can prevent or delay the development of chronic kidney disease into uremia after ten or twenty years, it will bring hope to many kidney patients and save many families! I even feel that this award can win the Nobel Prize in Medicine!"

"it is good!"

Lin Xiang was very excited to see everyone’s high enthusiasm, which was also the purpose of him convening a seminar with all the doctors in the department today!

"Since everyone has no objection, we will divide the department into two groups and officially begin the research on the effect of 'Kidney Toxin Clearing Dialysis Needle' in the clinical treatment of 'Stage III and Stage IV Kidney Disease' patients!"

Having said that, he paused!
“This requires everyone’s concerted efforts, a lot of clinical trials and patient follow-up!”

"Only in this way can we obtain the most accurate data on dosage, method of use, etc. of the 'Kidney Toxin Clearing Dialysis Needle' for kidney disease patients at all stages!"

"Only then can we have more accurate plans to treat each subsequent kidney patient in the future!"

"Of course, everyone in our department will have a share in the results of the project, and any journal we publish will be published in the name of the entire department. Good luck everyone!"

As soon as the words came out, the eyes of the doctors present became completely excited.

……

Tsingshan Pharmaceutical has completed the task of developing the "Kidney Toxin Clearing Dialysis Needle", but frontline clinicians such as Director Lin Xiang have begun new explorations.

They need to make this alternative needle, originally intended for dialysis patients, more widely available to more kidney patients.

Of course, this is a long process.

It may take three or five years for the medical community to finally come up with a treatment plan that is recognized by everyone and can better serve every kidney disease patient in the future.

That's the great thing about being a clinician.

A week later, the Nephrology Department of Chengdu Third People's Hospital suddenly published an article titled "Feasibility Report on the Application of Kidney Toxin Clearing Dialysis Needle in Renal Stage IV Patients" in the well-known domestic kidney journal - Chinese Journal of Nephrology.

The report fully disclosed for the first time the therapeutic effects and clinical data of "Shenduqing" on patients with stage III and IV kidney disease!

As soon as the article was published, it immediately caused a strong shock in the domestic kidney medicine community!

Everyone knows that stage one and two kidney disease can still be barely controlled!
Stage III and IV kidney disease is almost a process of chronic progression to uremia. The world has been studying kidney disease for 100 years!
There is no medical institution or pharmaceutical company in the world that can stop or significantly delay the progress of Phase III and Phase IV!

No one doubts it, everyone knows that Chengdu Third People's Hospital is the largest clinical trial center for "Kidney Toxin Clearing Dialysis Needle" and has a large amount of clinical usage data!
For a time, major domestic hospitals such as Zhejiang University, Ruijin Hospital and even Union Hospital began to contact the Third People's Hospital, hoping to send doctors to the Third People's Hospital's Nephrology Department to study and learn the clinical use of Shenduqing!
The news quickly spread abroad.

When the "Feasibility Report on the Application of 'Kidney Poison Clearing Dialysis Needle' in Patients with Stage IV Kidney Disease" published by the Nephrology Department of Sanren Hospital was reprinted by the top medical journal "The Lancet",

The foreign medical community, especially the foreign kidney medicine community, also caused a strong shock!

After hesitating for less than three seconds, Hopps, chief physician of the Department of Nephrology at the Royal London Hospital,

William, a top nephrologist at the Mayo Clinic in the United States,

Mueller, Charité National Hospital, Berlin, Germany

Chief doctors from six or seven of the world's top kidney hospitals, including Lee Ming-jen of the National Hospital of Singapore, have taken the initiative to express their desire to come to the Nephrology Department of the Third People's Hospital of Chengdu for a half-month academic exchange!
Everyone knows!

If "Kidney Toxin Clearing" really has a delaying effect on controlling chronic kidney disease, it will undoubtedly completely change all current treatment options for "chronic kidney disease"!

This is a historic subversion!

The feasibility report of Chengdu Third People's Hospital on the application of "Kidney Toxin Clearing Dialysis Needle" in "Chronic Kidney Disease" has completely ignited the strong attention of hundreds of millions of kidney patients suffering from kidney disease around the world, as well as countless top nephrologists to Kidney Toxin Clearing!

Zhang Yang was originally immersed in the excitement of the gratifying sales in the first month after the launch. However, after receiving calls from one hospital after another and reading the sensational report published by three doctors, Zhang Yang knew that "Shenduqing" was going to be a hit!

A week after the news spread around the world, Tsingshan Pharmaceutical's "Kidney Toxin Clearing Dialysis Replacement Needle" became famous in the global kidney disease circle!

Those patients with chronic kidney disease may still be watching and still doubting, but dialysis patients have already taken action!
"Although I already have uremia, is there any chance that I can be saved?!"

For a time, the usage rate of renal dialysis replacement needles began to soar!
……

PS: This part does not count as money.

I decided not to stay up late and write during the day.

From now on, one chapter will be updated at 6pm every day, and if it is a double update, another chapter will be updated at 10pm.

Take care of yourself, everyone.

(End of this chapter)

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