After being fired, I became the light of medicine

Chapter 139 Goodbye Jiang Yong. (Subscribe)
Fang Hanliang decided to return to China and join Tsingshan Pharmaceutical more than half a year ago, and he began to handle his resignation matters at BI Company in the past six months.

The BI company did not make things difficult for him, and after a six-month work handover, he was able to resign smoothly.

After returning to China, he originally wanted to start work quickly, but Zhang Yang suggested that he spend a few days with his family and give the company some time to help him find a suitable residence.

Fang Hanliang was a man of sentimental character. After hearing how thoughtful Zhang Yang was, he decided to bring his parents to Chengdu. He then took the opportunity to look for houses while accompanying his parents for a few days and planned to settle down in Chengdu.

Therefore,
Zhang Yang did not rush to contact Fang Hanliang to ruin his rare vacation. Instead, it was not until three days later that Fang Hanliang, who had just finished his vacation, came to Zhang Yang's office.

"Fang Bo (Doctor), how was your house search these past ten days? Have you chosen one?"

"Well, I've chosen."

Fang Hanliang nodded with a smile on his face, looking quite satisfied.

"It's in Jinlin Peninsula in the south of the city. The balcony and living room are quite large, and the layout is very suitable. My parents also liked it very much, and I was also very satisfied, so I bought it without much hesitation!"

"As long as you're satisfied."

Zhang Yang also laughed.

Of course, he did not doubt Fang Hanliang's financial resources. He had worked in a top foreign pharmaceutical company for so many years and his father was a university professor, so it was more than enough for him to buy a house.

The two chatted for a while before Zhang Yang gradually got to the point.

"By the way, Fang Bo, I have something else I want to consult you about. Do you know about the drug called 'BI-Toxin Filtration Catalyst' produced by BI, your previous company?"

"'BI-Toxin Filtration Catalyst'? What's that?"

Fang Hanliang was a little surprised and didn't quite understand what Zhang Yang meant by suddenly asking this.

"Nothing."

Zhang Yang didn't beat around the bush and explained:
"The Phase I clinical data of this drug came out a few days ago. The clinical data is not very good, with only a 2-3% improvement effect."

"I have heard Vice President Hans's presentation at the Global Kidney Summit. Their laboratory expected data is 7%, right? Now the clinical data is only 2-3%. Do you think they have a chance to increase it to 7% through subsequent continuous improvements?"

Fang Hanliang understood instantly, but he did not answer immediately. Instead, he frowned, took out his cell phone from his bag and swiped it quickly.

"Are you looking for their Phase I clinical data?"

"Ah."

"here has."

Zhang Yang then handed the pad on the desk to Fang Hanliang and said slowly:

"I have downloaded all the data. It is all on the tablet. Please take your time to read it. There is no rush."

At this moment Fang Hanliang was really surprised. He didn't expect Zhang Yang to attach so much importance to this drug.

But he didn't say much. His many years of working experience in Germany have made him develop a rigorous habit of "looking at the data before speaking".

About fifteen minutes later, he slowly raised his head and handed the tablet back to Zhang Yang.

"Mr. Zhang, although I did not participate in the research and development of this drug at BI, this clinical data is indeed somewhat lower than expected; I have talked with many core researchers of this drug, and their psychological expectation is at least 5% or more."

"Back to your question, will they have a chance to increase the dosage to 7% by adjusting the drug ingredients? To be honest, I don't know. It requires a bit of luck."

"But what is certain is that I have learned about this drug, and I think there is nothing wrong with the design of this drug!"

Zhang Yang nodded slightly without responding, indicating Fang Hanliang to continue talking in depth.

Seeing this, Fang Hanliang continued:
"There are mainly two types of molecular substances in the blood of patients with uremia, one is a large molecule and the other is a small molecule."

"The current working principle of hemodialysis is that it can only remove harmful small molecules, such as metabolites urea, creatinine and uric acid."

"Another example is the excess water in the body, potassium ions, sodium ions and other trace elements taken into the body from food."

"Another macromolecular substance..."

"Hemodialysis is unable to remove large molecules, the most common of which is low-density lipoprotein (LDL), but the most important and toxic are 'protein-bound toxins'."

"These toxins are tightly bound to proteins in the blood to form large molecular complexes, making it difficult for the dialysis membrane to effectively remove them. Over time, they will accumulate in the body in large quantities and continue to cause harm to dialysis patients."

"The core drug ingredient of 'BI-Toxin Filter Catalyst' is to quickly decompose and break down large molecular complexes, turning them into small molecules, thereby improving filtration efficiency."

"This idea is correct, and the laboratory data is also good. According to common sense, clinical data should not have such a large error. It's really strange..."

As he spoke, he shook his head:

"To be honest, Mr. Zhang, I don't know the specific reason why the data is so different. It's possible that even their R&D team doesn't know where the problem lies."

“So, luck is needed.”

Zhang Yang sighed slightly. This is the real drug development process.

The laboratory data is good, but when it comes to clinical practice, you will encounter some strange problems. What is even more despairing is that you don’t even know what went wrong.

If you are lucky, it can be discovered quickly. If you are unlucky, it is normal for it to be stuck for three to five years.

"All right……"

Zhang Yang did not continue discussing this topic and pondered for a moment:

"To be honest, I am very interested in this drug."

"Given that you have worked at BI for so many years, do you think it is possible for us to buy out the patent for this drug from them?"

"Buy out the patent?"

This time Fang Hanliang had almost no hesitation and kept shaking his head.

"Mr. Zhang, as far as I know, 'BI-Toxin Filter Catalyst' is one of the three key R&D projects within BI. They have invested a lot of manpower and R&D funds."

"Even if the current Phase I clinical data is not ideal, it is impossible for them to sell the patent for this drug now."

"Unless, they continue to test and still can't solve this problem. But if that's the case, what's the point of buying it?"

Zhang Yang let out a breath, this was indeed the case.

However, he was indeed very interested in this drug, and he would not be willing to buy it and study it, so he had to say:

"Okay, let's wait until they have more clinical data."

"Ah."

The two's discussion about BI's "toxin filtering catalyst" ended quickly, and Fang Hanliang officially joined the company to start building his own R&D team.

This was the task Zhang Yang assigned to him. There was no need to rush into launching a drug development project. He should first familiarize himself with the personnel and build up the team.

Zhang Yang temporarily hid his interest in "BI-toxin filtering catalyst" and waited for the follow-up. Zhang Yang's work focus began to shift to the clinical trial of "Kidney Toxin Clearing Dialysis Replacement Needle" in China, but soon his work plan was interrupted by another matter.

The "liver cell activator" with 50% effectiveness, the Liver Protection and Regeneration Capsule, which was previously applied for as a health product, is ready to be put on the market for sale.

This drug has exactly the same ingredients as the "LivClearX" on the market in the United States, but compared to the U.S. market price of up to US$1500, Zhang Yang finally set the domestic price at 350 yuan per bottle.

On the one hand, fatty liver is not really considered a major disease in China, and it can be eliminated through weight loss, diet control, etc. If the price is too expensive, probably no one will buy it.

On the other hand, in Zhang Yang's words, this can be considered a benefit that Qingshan Pharmaceutical gives to the Chinese people, allowing everyone to afford truly effective liver-protecting drugs.

of course,

In order to take care of the sales of LivClearX in the US market, Zhang Yang did not advertise that the drug had exactly the same ingredients as "LivClearX" and did not even advertise it to the outside world. He only briefly introduced that it had certain liver-protecting effects on fatty liver and alcoholic liver.

Even so,
Because "LivClearX" was so popular in China before, the "Liver Protection and Regeneration Capsules" still attracted everyone's attention when they were first launched on the market, especially the reasonable price of 350 yuan per bottle, which made many ordinary people willing to buy it to try it out.

Tsingshan Pharmaceutical also opened an official store on JD Pharmacy. In just two days, it received nearly 5000 orders without any publicity.

Zhang Yang was quite satisfied with this data.

After paying attention to this little episode, Zhang Yang turned his attention back to the most important project at present - the Phase III domestic clinical trial of the "Kidney Toxin Clearing Dialysis Replacement Injection". But when he was looking at the latest week's clinical data, a familiar yet unfamiliar phone call came in.

Lin Xiang.

If there hadn't been a note on the phone, he would have almost forgotten who this familiar name belonged to.

He is the director of the Nephrology Department of Chengdu Third People's Hospital, and is also the main source of subjects for the Phase III clinical trial of "Kidney Toxin Clearing Dialysis Needle".

Seeing Lin Xiang’s call, Zhang Yang felt inexplicably nervous. Could something have gone wrong with the clinical trial?

"Hello, Director Lin."

"Hello, Mr. Zhang. Hello, I hope I did not disturb you."

The relaxed tone made Zhang Yang relax a lot, but Lin Xiang's sudden call made him a little curious.

What is it all about?
"No need to bother you, Director Lin, what can I do for you?"

"It's nothing particularly important. I just met an acquaintance at the clinical trial center today. We've met together before, so I called you to ask about it."

acquaintance?

Have you met together?
Zhang Yang was a little surprised. At this moment, Lin Xiang continued:

"He's the man with uremia whom we met in the dialysis room last time. His name is Jiang Yong."

"Didn't you write him a note asking him to come to work in your company? I ran into him at the clinical trial center today, and he also signed up for the Phase III clinical trial of 'Shenduqing'."

"So I'm a little confused. Logically, he already works in your company, so he shouldn't be participating in clinical trials..."

"Jiang Yong?"

Zhang Yang was stunned. Lin Xiang only knew that he had given Jiang Yong a note to come to work, but what Lin Xiang didn't know was:
Jiang Yong later wanted to divorce his wife because she cheated on him. He quit his job and ran to the Shenzhen Stock Exchange to seek an explanation. Unexpectedly, after a few months, he is back now?

Is it done?
Thinking of this, Zhang Yang was even more surprised. He remembered that he had told Jiang Yong that if he didn't find a job after returning, he could come back to work.

But in the past half month, I haven't seen Jiang Yong on my way to and from get off work, and no one has reported Jiang Yong's situation to me. It is very likely that he has not returned to work.

After a moment, thinking that I was still on the phone, I had to say:
"Director Lin, Jiang Yong is not working in our company now, but..."

"I do have something I want to talk to him about. When is the next time he comes to the hospital to receive medication?"

"Isn't he working at your company? Oh, his next visit to the hospital is tomorrow morning at 9 o'clock."

"Ok."

Zhang Yang exchanged a few more words with Director Lin and then hung up the phone.

The next day, he arrived at the clinical trial center of Chengdu Third People's Hospital early.

As soon as he arrived, his old acquaintance, Deputy Director Feng Gang, welcomed him into the office.

After a cup of fragrant Biluochun was placed on Zhang Yang's table, Director Feng Gang looked at Zhang Yang with a smile on his face:
"Mr. Zhang, you need to come more often. I haven't seen you for almost half a year. I'm afraid you have almost forgotten about us old friends."

"Director Feng, how could we forget you? We are constantly bothering you with our various clinical projects!"

As he spoke, Zhang Yang gently placed the ten boxes of "Liver Protection and Regeneration Capsules" that he had prepared in advance on Feng Gang's desk.

"You know, this stuff really has a good protective effect on the liver. Director Feng often socializes, and eating this is good for the liver."

"It just happened to be on the market, so I'll get you a few boxes. I'll bring more to you when you've finished eating them."

Feng Gang was shocked and quickly refused.

"Mr. Zhang, how can this be possible! You can take it, you can take it. You know me. I never accept gifts."

Zhang Yang was amused and laughed:
"Director Feng, I know you don't accept gifts, but do you think I'm bribing you?"

"Besides, have you ever seen anyone send medicine as a bribe?"

Feng Gang was stunned for a moment, then reacted.

Yes, if it was other pharmaceutical companies that took something, it could be said that they had other intentions, but Zhang Yang in front of him...

Qingshan Pharmaceutical never thought of giving gifts when it was first started. With its current reputation in China, there is no need to give gifts at all. In other words, there is no need to bribe a director of his level at all.

Suddenly, his heart warmed and he completely understood what Zhang Yang meant.

This was a small gift he gave to himself as a friend.

but……

After hesitating for a moment, he pushed it away and refused:
"Mr. Zhang, thank you for treating me as a friend, but I really can't accept these things. If I need them, I'll just buy them, and you can give me a discount then."

"By the way, you didn't come here just to give me a gift today, did you?"

Zhang Yang was a little surprised by Feng Gang's rejection, but soon he became more respectful.

He didn't dwell on it any more, and immediately explained his purpose:
"Today I'm mainly here to look for an employee from my previous company who is currently participating in a clinical trial of 'Kidney Du Qing'."

As he spoke, Zhang Yang looked at his phone. The time had just come to 9 a.m., and this batch of subjects should have arrived.

He then followed Feng Gang to the hall of the clinical trial center and saw Jiang Yong who was preparing to draw blood.

Jiang Yong also noticed Zhang Yang and quickly looked to the other side.

After a moment, Jiang Yong looked at Zhang Yang who was walking in front of him and whispered:
"boss Zhang……"

(End of this chapter)