As a mage, I just want to pursue the truth

Chapter 66 A New Protein

Jiangcheng has always wanted to develop the biopharmaceutical industry, and the planning of its Optics Valley Industrial Park includes the biopharmaceutical industry.

For example, in 2009, the international giant Pfizer Pharmaceuticals was introduced to establish a biopharmaceutical R&D center in Optics Valley.

Including China's WuXi AppTec, Sinopharm Group, and Germany's Berlin Chemie, all have R&D centers in Optics Valley.

However, there are no well-known giants in the biopharmaceutical industry in Optics Valley. Optics Valley wants to build a trillion-dollar biopharmaceutical industry chain, but there is no company with enough influence and strength to serve as a leader.

Just as Hangzhou has Ali, so the city's Internet industry is exceptionally developed. It is no exaggeration to say that Ali, a giant, has driven the entire Hangzhou's Internet economy.

Li Miaomiao declined politely on the other end of the phone: "Our headquarters is in Gusu, and Jinling has always wanted to poach us."

"Every time our general manager Cheng Gang went to Jinling for a meeting, the Jinling leadership said overtly or covertly that a company like ours should go to Jinling so that we can have more room to develop."

"The problem is that Zheng Li thinks Suzhou is pretty good, so why should he move around? He likes quiet and clean places, and Suzhou's high-tech park is more in line with his requirements."

"As for Guanggu, you know that it has been under construction all the time, so I'm afraid it won't be very quiet."

"You can tell the leaders of the East Lake New District that there is no way that Gusu or even the province will let us go."

Now it was Li Xulin's turn to sigh: "The leaders of Jiangcheng told me that as long as you are willing to move, they will take care of all matters at the government level."

For an enterprise of the level of Ke Chuang Biotechnology, the annual tax revenue is a considerable financial income for the city, and more importantly, it enhances the city’s overall influence.

From bringing business to upstream and downstream biomedical companies in Jiangcheng, to retaining high-end talent resources from Jiangcheng's university cluster, and then to having a leader in the development of the biomedical industry, it would be of great significance if Ke Chuang Bio could return to Jiangcheng.

Of course, Suzhou will definitely not agree to let Ke Chuang Bio go. Suzhou's biopharmaceutical industry is also developing rapidly, especially after Ke Chuang Bio's rocket-like rise in the past two years, Suzhou's biopharmaceutical industry has developed even more rapidly.

For the city, great businesses can only wait.

Shenhai has always been criticized for not having Internet genes. Even former Internet giants like Shanda went from being at their peak to being on the verge of collapse under Shenhai.

Compared to the north
Li Miaomiao: "The problem is that I don't have the final say. Zheng Li is not interested in relocation. I can bring it up, but he probably won't agree."

"If we set up a research and development center in Jiangcheng, I am confident that I can convince him."

"I have talked with Zheng Li about the future application of brain-computer connection in some special medical fields and certain specific fields. This part of the research can be carried out in Jiangcheng."

The famous Area 51 is located in Lincoln County in southern Nevada, America.

There are warning signs everywhere on the road leading to Area 51, and America does have a secret laboratory located there.

After Simmons faked his death, he was transferred here by the American military. After completing the weekly routine blood test, Simmons came to the room where Sassoon, the head of biological research, was.

"Professor, how are you feeling today?"

Simmons: "I feel very good. I didn't expect that I could embark on such a fantastic journey at the end of my life. From the moment I injected the magic brain, I felt that my brain went back to when I was 20 years old."

"Nothing can make an old man more happy than returning to youth. Even though I have changed my environment and said goodbye to my family forever, I feel very good now."

Sassoon, who has a PhD in both biology and psychology, encouraged people to keep this attitude.

"From your test results, your cells have indeed regained their youthful activity. Your feeling is correct."

"Take the neural stem cells in your brain, for example, which decrease with age.

Previously, we believed that this process was related to the depletion of genetic information, which led to the aging of cells.

In recent years, we have discovered that the aging of neural stem cells may also be related to certain mediators.

In addition to its function of anchoring chromatin around the cell nucleus, Lamins also contribute to the aging of neural stem cells.

Mutations in Lamin A (LA), encoded by LMNA, disrupt nuclear shape and function and lead to cell senescence.

The intrinsic regulatory mechanism of age-dependent changes in hippocampal neural stem cell activity mediated by lamin B1 is also an important cause of neural stem cell aging. "

Simons was a little confused. He is an expert in mathematics and finance, and is still taking supplementary courses in biology. "I'm sorry, I may not understand these professional terms very well."

Sassoon concluded in two sentences: "The neural stem cells in your body have regained activity after the injection of the magic brain, but this recovery is most obvious at the brain cell level, and not so obvious in your other human cells."

Simmons: "I am very satisfied to be able to live out my old age so clearly, and I feel that my perception of the outside world is much stronger than before."

"I can feel not only the flow of wind and temperature changes, but also the changes in the intensity of radiation and light fluctuations, and even the flow of cells in my body."

Sassoon:

“I have to admit that Merlin’s magic brain is a magical thing. It induces the further differentiation of the neuronal cells in your body.

Neurotransmitter release at vertebrate neuronal synapses is guided by action potentials, whereas at sensory synapses, release is driven by receptor potentials that direct graded cellular throughput.

Neurotransmitter release allows rapid communication between neurons in higher organisms.

In neurons, release is restricted to specialized, electron-dense regions called active zones, represented by disc-like structures covered with synaptic vesicles.

The synaptic vesicles in your neurons have taken on shapes we've never seen before
At the junctions between nerve cells, active zones form what look like long, thin ridges lined on both sides with synaptic vesicles of a unique structure.

And in sensory cells like hair cells and photoreceptors in your body, active zones appear as irregular manifolds surrounded by vesicles. Despite the differences in shape and structure, all active zones contain voltage-gated calcium channels and proteins that mediate and regulate exocytosis and endocytosis.

A series of structural proteins, like piccolo and bassoon, set in the cellular framework, form the skeleton of the active zone cytosol, organizing a dynamic pool of vesicles around this area

Synaptic vesicles are lipid bilayer structures with a diameter of 40-100 nm and are filled with neurotransmitter molecules.

The membranes of neuronal and sensory cell vesicles have developed a novel class of proteins that play a role in vesicle regeneration, trafficking, and exocytosis/neurocytosis.

This novel protein leads to fast synaptic exocytosis, such as that of neurons, photoreceptors and hair cells, which occurs within milliseconds after calcium influx, and we have observed 0.5 ms or less.

Your observation value alone has surpassed all creatures on the blue planet. It is incredible. A new protein is helping the nerve signals and sensory cells in your body to flow."

(End of this chapter)